The free passage of I 131 antipyrine through brain as an indication of A‐V shunting

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Abstract
Following rapid intravenous injection of I131-labeled antipyrine large arteriovenous shunts can be detected by an initial peak on the curve representing the cranial isotope content. This peak is attributed to the failure of the isotope passing through the shunt to equilibrate with brain water, as normally occurs upon passage through the brain capillary bed. The test is extremely atraumatic and is suggested as a screening test or as a means of repeatedly studying the physiology of A-V shunting.

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