MEASUREMENT OF THE CEPHALIC AND CEREBRAL BLOOD FLOW FRACTIONS OF THE CARDIAC OUTPUT IN MAN*

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Abstract
The application of the indicator fractionation technique to the measurement of the cephalic blood flow in man (iodol31-antipyrine) and to the measurement of noncerebral cephalic blood flow (K42) is described. Results are given on the cephalic and extracerebral cephalic blood flow fractions of 23 normal and 11 hyperventilating persons. Values for cerebral blood flow fractions are calculated in these individuals. The cerebral blood flow fraction in normal persons by this technique is 11% of the cardiac output; hyperventilation reduces this figure to 6%. Potential sources of error in the indicator fractionation technique in the cerebral blood flow measurement are described.

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