Influence of Gestation and Lactation on Kadiostrontium-Induced Malignancies in Mice: I. Incidence, Distribution and Characteristics of90Sr-Induced Malignancies

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Abstract
Gestation and lactation during carcinogenesis in female mice bring about a significant increase in the latency period of bone sarcoma and a similarly significant reduction in the total number of skeletal tumors as compared with the unmated control group. A distinct influence on tumor location was also seen, with lower tumor frequency in the lumbar and sacral vertebrae and pelvic bones. Damage to the blood and blood forming organs was reduced in the gestating and lactating groups of mice. However, the frequency of leukemia increased, and to a certain degree also the frequency of tumors in soft tissues.

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