A direct modeling approach to the early renal vascular transit of 99m Tc chelates

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Abstract
Delay channel integral methods are develpoed and applied for analyzing human renal scintiangiographic data produced after peripheral venous injection of a 99mTc chelete. The results include information for two renal vascular compartments (C1, C2) and a residual compartment (Cr). Each vascular component is associated with a fraction of the total renal plasma flow (A1, A2) and a mean transit time (T1, T2). The residual compartment has the residual plasma flow fraction Ar. The results obtained in 40 normal kidneys are presented and compared theoretically to the results from other methods.