Abstract
Maturation of carbonic anhydrase activity has been investigated in erythrocytes, gastric mucosa, kidney cortex, pancreas and lung tissues of the rhesus monkeys from 70 days of gestation to one year of age. Activity of brain tissue (cortical gray matter) was also assayed in the older animals. Significant maturation of activity in erythrocytes, gastric mucosa and renal cortex was noted during the investigation. Definite activity seemed present in fetal lung and pancreas, but values in the one year animals were minimal as were cerebral gray matter activities at one year. These results are in general agreement with reported studies in the human fetus and infant.