The Sparing Action of Protein on the Pantothenic Acid Requirement of the Rat

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Abstract
Studies of urinary and fecal excretion of pantothenic acid by deficient rats maintained on purified diets differing in casein level gave the following results: Neither increased intestinal synthesis of pantothenic acid as measured by fecal excretion nor a decreased vitamin loss by urinary excretion are responsible for the sparing action of high casein diets on the pantothenic acid requirement of the rat. The pantothenic acid content of the casein used in the purified diet while exercising an effect can not fully account for the protective action of such diets.