Identification and characterization of a self-regulated repressor of translocation of the Tn3 element.
- 1 August 1979
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 76 (8) , 4020-4024
- https://doi.org/10.1073/pnas.76.8.4020
Abstract
Gene fusions [in Escherichia coli] that bring expression of the lacZ gene under control of transcriptional and translational signals within the transposable element Tn3 were used to study regulation of Tn3-specified proteins. A gene encoding a 21,355-MW peptide that represses translocation of Tn3 and acts at the level of transcription to regulate its own synthesis was identified and sequenced; amber, missense and cis-dominant (operator-constitutive) point mutations in this gene were isolated and characterized.This publication has 35 references indexed in Scilit:
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