The Spermicidal Powers of Chemical Contraceptives. VI. An Improved Test for Suppositories

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Abstract
1. A fluid is described in which cavy sperms react to the most diverse substances almost exactly as do human sperms in human semen. This fluid, called albumen-saline, consists of:0·9% sodium chloride solution … 0·7 c.c. Egg-white … … … … 2·3 c.c.2. A detailed description is given of a new technique for comparing the spermicidal powers and rate of disintegration of suppositories (including foam tablets).3. The new test differs from the old chiefly in allowing only five minutes for the spermicide to act, and in requiring the actual killing of the sperms and not only their immobilisation.4. Of the commercial suppositories tested, Rendell and Finil are the most spermicidal, followed by Vimule, Speton, Semori, Prorace (chinosol) and Martindale, in that order. None of them is sufficiently spermicidal to encourage complete reliance in the absence of other contraceptive methods.