Methotrexate in lymphomatoid papulosis

Abstract
The effect of weekly methotrexate treatment (5-25 mg orally) was studied in 3 patients with lymphomatoid papulosis. In all 3 patients a good clinical effect was obtained. Skin biopsies revealed no sign of lymphomatoid papulosis after treatment. Methotrexate appears to be effective in controlling lymphomatoid papulosis and is possibly superior to PUVA [psoralen plus UVA] in this respect.