Preoperative intraparietal (intra-incisional) cefoxitin in abdominal surgery

Publisher Website
Google Scholar
Abstract
The effect of preoperative intraparietal (intra‐incisional) injection of cefoxitin along the site of the intended incision on the incidence of wound infection has been investigated by a randomized prospective study of 181 consecutive patients undergoing abdominal surgery. A significant reduction in wound infection was evident in the cefoxitin‐treated group (4·4 per cent) when compared with controls (16·7 per cent) (χ2 = 6; P = 0·02). Administration of antibiotic by this route did not delay wound healing or produce any undesirable sequelae.