Inhibition of squalene synthase in vitro by 3-(biphenyl-4-yl)-quinuclidine
- 14 June 1996
- journal article
- research article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 51 (11) , 1489-1501
- https://doi.org/10.1016/0006-2952(96)00090-1
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- Effect of squalestatin 1 on the biosynthesis of the mevalonate pathway lipidsBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1994
- Cloning, expression and characterisation of the cDNA encoding human hepatic squalene synthase, and its relationship to phytoene synthaseGene, 1993
- Overexpression, Purification, and Kinetic Characterization of a Carboxyl-Terminal-Truncated Yeast Squalene SynthetaseArchives of Biochemistry and Biophysics, 1993
- Yeast Squalene Synthase: Expression, Purification, and Characterization of Soluble Recombinant EnzymeArchives of Biochemistry and Biophysics, 1993
- Cholesterol lowering and mortality: the importance of considering initial level of risk.BMJ, 1993
- Conservation between human and fungal squalene synthetases: similarities in structure, function, and regulation.Molecular and Cellular Biology, 1993
- The first potent inhibitor of squalene synthase: a profound contribution of an ether oxygen to inhibitor-enzyme interactionJournal of the American Chemical Society, 1991
- Isoprenyl phosphinylformates: new inhibitors of squalene synthetaseJournal of Medicinal Chemistry, 1991
- Regulation of the mevalonate pathwayNature, 1990
- Isoprenoid (phosphinylmethyl)phosphonates as inhibitors of squalene synthetaseJournal of Medicinal Chemistry, 1988