Characterization of Human Heterophile Antibodies Apparently Induced by Alloimmunization
- 1 September 1977
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 33 (3) , 143-149
- https://doi.org/10.1111/j.1423-0410.1977.tb02246.x
Abstract
Human heterophile antibodies reactive with various tissues of different species [e.g., rat and mouse] may be detected by indirect immunofluorescence. Results of screening sera obtained after Rh immunization and before and after blood transfusion and renal transplantation suggest that such antibodies can appear following alloimmunization of group A and O individuals. Eleven positive sera selected for detailed study had anti-B isohemagglutinins together with rat erythrocyte agglutinins. Absorption studies suggested that there may be some relationship between the group B antigen and the rat antigen concerned but the precise explanation for alloimmunization remains to be determined.This publication has 8 references indexed in Scilit:
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