Protein Engineering
- 11 February 1983
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 219 (4585) , 666-671
- https://doi.org/10.1126/science.6572017
Abstract
The prospects for protein engineering, including the roles of x-ray crystallography, chemical synthesis of DNA, and computer modelling of protein structure and folding, are discussed. It is now possible to attempt to modify many different properties of proteins by combining information on crystal structure and protein chemistry with artificial gene synthesis. Such techniques offer the potential for altering protein structure and function in ways not possible by any other method.Keywords
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