CHEl UF Serum Cholinesterase Phenotype in Whites and Non-Whites from Southern Brazil as Determined by a New Method
- 1 January 1991
- journal article
- research article
- Published by S. Karger AG in Human Heredity
- Vol. 41 (2) , 103-106
- https://doi.org/10.1159/000153986
Abstract
A sample of 251 Whites and 818 Non-Whites, from Curitiba (southern Brazil), was typed with a new method with the aim of estimating the frequency of the CHE1*Fallele. The frequency of this allele did not differ between Whites (0.60 +/- 0.34%) and Non-Whites (0.49 +/- 0.17%), being estimated as 0.51 +/- 0.15% for the whole sample. The use of the inhibitors DL-propranolol and RO2-0683 with alpha-naphthylacetate as substrate (at 37-degrees-C) was efficient for discriminating between the CHE1 U and CHE1 UF phenotypes.Keywords
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