Structural basis of transcription: α-Amanitin–RNA polymerase II cocrystal at 2.8 Å resolution
Open Access
- 22 January 2002
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 99 (3) , 1218-1222
- https://doi.org/10.1073/pnas.251664698
Abstract
The structure of RNA polymerase II in a complex with the inhibitor α-amanitin has been determined by x-ray crystallography. The structure of the complex indicates the likely basis of inhibition and gives unexpected insight into the transcription mechanism.Keywords
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