Neurologic Disorders in Renal Failure

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Abstract
Uremic NeuropathyNeuropathy occurs in at least 65 per cent of patients who are about to begin dialysis for chronic renal failure,70 and is perhaps the most common neurologic consequence of chronic uremia. It was described by Asbury and his colleagues71 as a distal, symmetrical, mixed, sensorimotor polyneuropathy, affecting the lower limbs to a greater extent than the upper limbs. It is clinically indistinguishable from the neuropathies associated with chronic alcohol abuse, diabetes mellitus, and lupus erythematosus, to name but a few. The rate of progression, severity, prominence of motor or sensory signs, and prevalence of dysesthesia are quite variable. . . .

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