Screening for the potential of a drug candidate to cause idiosyncratic drug reactions
- 2 September 2003
- journal article
- review article
- Published by Elsevier in Drug Discovery Today
- Vol. 8 (18) , 832-837
- https://doi.org/10.1016/s1359-6446(03)02816-2
Abstract
No abstract availableKeywords
This publication has 28 references indexed in Scilit:
- Chemically Reactive Metabolites in Drug Discovery and DevelopmentPublished by Taylor & Francis ,2003
- Mechanisms of Troglitazone HepatotoxicityChemical Research in Toxicology, 2003
- Hepatotoxicity with ThiazolidinedionesDrug Safety, 2001
- A Role for Bioactivation and Covalent Binding within Epidermal Keratinocytes in Sulfonamide-Induced Cutaneous Drug ReactionsJournal of Investigative Dermatology, 2000
- Immunological Principles of Adverse Drug ReactionsDrug Safety, 2000
- New Concepts in Immunology Relevant to Idiosyncratic Drug Reactions: The “Danger Hypothesis” and Innate Immune SystemChemical Research in Toxicology, 1999
- Tolerance, Danger, and the Extended FamilyAnnual Review of Immunology, 1994
- Mass spectrometry in the analysis of glutathione conjugatesJournal of Mass Spectrometry, 1993
- The Immunologic and Metabolic Basis of Drug HypersensitivitiesAnnual Review of Pharmacology and Toxicology, 1988
- Toxic effects of isoniazid in tuberculosis chemoprophylaxis. Role of biochemical monitoring in 1,000 patientsJAMA, 1979