New carbon-linked azole oxazolidinones with improved potency and pharmacokinetics
- 1 January 2007
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 17 (2) , 337-340
- https://doi.org/10.1016/j.bmcl.2006.10.063
Abstract
No abstract availableKeywords
This publication has 10 references indexed in Scilit:
- Identification of 4-Substituted 1,2,3-Triazoles as Novel Oxazolidinone Antibacterial Agents with Reduced Activity against Monoamine Oxidase AJournal of Medicinal Chemistry, 2005
- The safety and efficacy of linezolid in orthopaedic practice for the treatment of infection due to antibiotic-resistant organismsExpert Opinion on Drug Safety, 2004
- The synthesis and antimicrobial evaluation of a new series of isoxazolinyl oxazolidinonesBioorganic & Medicinal Chemistry Letters, 2004
- Monoamine oxidases: to inhibit or not to inhibit.Mini-Reviews in Medicinal Chemistry, 2003
- Substituent Effects on the Antibacterial Activity of Nitrogen−Carbon-Linked (Azolylphenyl)oxazolidinones with Expanded Activity Against the Fastidious Gram-Negative Organisms Haemophilus influenzae and Moraxella catarrhalisJournal of Medicinal Chemistry, 2000
- The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycinAntimicrobial Agents and Chemotherapy, 1997
- Synthesis and Selective Monoamine Oxidase B-Inhibiting Properties of 1-Methyl-1,2,3,6-tetrahydropyrid-4-yl Carbamate Derivatives: Potential Prodrugs of (R)- and (S)-NordeprenylJournal of Medicinal Chemistry, 1996
- Condensed heteroaromatic ring systems. XIX. Synthesis and reactions of 5-(tributylstannyl)isoxazolesTetrahedron, 1991
- Antibacterials. Synthesis and structure-activity studies of 3-aryl-2-oxooxazolidines. 2. The "A" groupJournal of Medicinal Chemistry, 1990
- Antibacterials. Synthesis and structure-activity studies of 3-aryl-2-oxooxazolidines. 1. The B groupJournal of Medicinal Chemistry, 1989