THE BLOOD PYRUVIC ACID LEVEL IN PATIENTS WITH STRESS HYPERGLYCAEMIA AND DIABETES MELLITUS

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Abstract
The fasting blood pyruvic acid (BPA) was determined in patients exhibiting fasting hyperglycemia. In 19 patients with uncomplicated diabetes mellitus the BPA level was normal. In 10 diabetic patients suffering from severe complications the level was moderately elevated. But it was also elevated in 26 non-diabetic patients suffering from the same disorders. The rise in BPA level which accompanied the acute stage of severe disorders was regarded as a stress phenomenon. It was concluded that normal fasting BPA levels were characteristic of moderate diabetes mellitus and that elevated BPA levels in patients with hyperglycemia, in the absence of stress and other causes of hyperpyruvicemia, suggest steroid diabetes.