Some Effects of Depletion and Repletion in Proteins on Body Fluids in Adult Dogs.

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Abstract
Total circulating plasma albumin decreased markedly, but total circulating globulins decreased only slightly below control values in protein-depleted dogs. These changes were accompanied by a reduction in plasma vol. and an increase in available fluids. The nutritional edema was corrected rapidly by repletion. In the depleted dog, less urinary N was excreted than in the normal control. During repletion, the excretion increased gradually as the result of decreased retention of dietary N and increased excretion of N from the body stores.