Corticosteroids for elderly patients with breast cancer

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Abstract
Ninety‐one assessable elderly women (⪖65 years) with advanced breast cancer were treated with prednisolone 15 mg (or cortisone 75 mg) daily after primary endocrine treatment (estrogens, androgens or tamoxifen). Thirteen (14%) achieved an objective regression, and 19 (21%) others showed no change for ⪖six months. Hence, 32 patients (35%) had control of disease for about one year. Responses were mainly in soft tissue and skeletal lesions and were independent of response to prior endocrine treatment. Toxicity was low. Low‐dose corticosteroid treatment is of value in controlling advanced breast cancer in elderly women.

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