T Cell Immune Function in Newborn Infants
- 1 January 1980
- journal article
- research article
- Published by S. Karger AG in Neonatology
- Vol. 37 (1-2) , 8-14
- https://doi.org/10.1159/000241250
Abstract
T cell immune function in 20 newborn infants was investigated. Previous studies showing increased spontaneous transformation and higher 3H-thymidine incorporation at lower PHA concentration in newborn infants were confirmed. A net increase in the number of active E rosette-forming lymphocytes and a slight decrease in the percentage of total E rosette-forming cells was also found. Our results suggest the presence of a subpopulation of activated T lymphocytes in the peripheral blood of newborns during the first days of life. Possible mechanisms of this activation are discussed.Keywords
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