CAPNOSPLENOPORTOGRAPHY

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Abstract
The use of carbon dioxide gas as a radio-negative contrast agent in splenoportography under experimental conditions is reported.The portal venous system in dogs was studied in the normal, after partial and complete occlusion of the portal vein, and in simulated portal hypertension. Comparative serial roentgenograms were made employing 6o per cent methyiglucamine diatrizoate and carbon dioxide gas.Splenoportography with carbon dioxide gas demonstrates partial or complete occulusios of the portal vein either directly or via collateral vessels. Similar results are not reproduced consistently using conventional positive contrast agents when the blood flow is mainly hepatofugal.In artificially induced portal venous hypertension carbon dioxide splenoportography demonstrates very well the patency of the portal vein. Using 6o per cent methyl-glucamine diatrizoate, there is poor visualization of the portal vein due to a mixing defect (streaming), dilution of contrast material and prolonged transit time in the port...