Problem of Hypothyroidism after I131Therapy of Hyperthyroidism
- 23 July 1964
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 271 (4) , 195-196
- https://doi.org/10.1056/nejm196407232710407
Abstract
THE introduction of radioactive iodine into clinical therapeutics in 1941 revolutionized the treatment of Graves's disease. It is now employed as the primary form of treatment for most of these patients, but in the early exploratory years, it was used cautiously because of fear that the radiation might cause thyroid cancer, leukemia or genetic damage. Hypothyroidism was recognized as an occasional complication and was accepted as a minor risk of treatment.The initial concern for the dangers of I131 have not in general been supported by experience, and arbitrary age barriers to its use have gradually fallen until now most . . .Keywords
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