Synthesis of Water-Dispersible Fluorescent, Radio-Opaque, and Paramagnetic CdS:Mn/ZnS Quantum Dots: A Multifunctional Probe for Bioimaging
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- 21 January 2005
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 127 (6) , 1656-1657
- https://doi.org/10.1021/ja0464140
Abstract
Ultra-small (3.1 nm) multifunctional CdS:Mn/ZnS core−shell semiconductor quantum dots (Qdots), which possess fluorescent, radio-opacity, and paramagnetic properties, have been shown here. To demonstrate in vivo bioimaging capability, a rat was administered endovascularly with Qdots conjugated with a TAT peptide. The labeling efficacy of these Qdots was demonstrated on the basis of the histological analysis of the microtome sliced brain tissue, clearly showing that TAT-conjugated Qdots stained brain blood vessels.Keywords
This publication has 10 references indexed in Scilit:
- Noninvasive Imaging of Quantum Dots in MiceBioconjugate Chemistry, 2003
- Applications of T-lymphoma labeled with fluorescent quantum dots to cell tracing markers in mouse bodyPublished by Elsevier ,2003
- Probing the Cytotoxicity of Semiconductor Quantum DotsNano Letters, 2003
- Tunable Near-Infrared Optical Gain and Amplified Spontaneous Emission Using PbSe NanocrystalsThe Journal of Physical Chemistry B, 2003
- Labeling of Biocompatible Polymer Microcapsules with Near-Infrared Emitting NanocrystalsNano Letters, 2003
- Ligand Design and Bioconjugation of Colloidal Gold NanoparticlesAngewandte Chemie International Edition in English, 2002
- Near-Infrared Fluorescent Nanoparticles as Combined MR/Optical Imaging ProbesBioconjugate Chemistry, 2002
- Up-converting phosphor reporters for nucleic acid microarraysNature Biotechnology, 2001
- High-Efficiency Intracellular Magnetic Labeling with Novel Superparamagnetic-Tat Peptide ConjugatesBioconjugate Chemistry, 1999
- Semiconductor Nanocrystals as Fluorescent Biological LabelsScience, 1998