The influence of theylocus on DDT resistance in the mosquitoAedes aegyptiL

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Abstract
The influence of the linkage group II locus y on DDT resistance in Aedes aegypti has been studied in crosses between the Trinidad resistant strain and QS susceptible strain. The y locus influences DDT resistance in both R/R and R/+ larvae. The effect of y may be interpreted as reducing the penetrance of R (RDDT1), which is also located on linkage group II. y+ is partially dominant and incompletely penetrant in its resistance-enhancing role (although in its pleiotropic effect on larval colour it is dominant and fully penetrant). Penetrance of y+ is influenced by an environmental factor, probably associated with the larval diet.The effect of y on resistance is evaluated in relation to other genetic influences on the expression of RDDT1.The significance of polymorphism at the y locus is discussed.