An Analysis of the Optimal Conditions for Perfusing an Isolated Rabbit Kidney with Homologous Blood
- 1 January 1983
- journal article
- research article
- Published by S. Karger AG in Kidney and Blood Pressure Research
- Vol. 6 (2) , 72-79
- https://doi.org/10.1159/000172883
Abstract
Isolated rabbit kidneys were perfused in a closed-circuit system with a number of media such a Krebs-Henseleit bicarbonate buffer with albumin, homologous platelet-free plasma, serum and whole blood. All of these media were unsatisfactory. In contrast, fresh blood deprived of platelets, leukocytes, floating lipoproteins, microaggregates and micro-clots did not cause vasoconstriction of the isolated kidney. Renal blood flow, glomerular filtration rate, urinary flow and glucose, cations and renal water reabsorption were approximately normal.Keywords
This publication has 14 references indexed in Scilit:
- Mechanism for renal tubular handling of angiotensinAmerican Journal of Physiology-Renal Physiology, 1979
- Metabolism of prostacyclin in the rabbit kidney.Journal of Biological Chemistry, 1979
- The Isolated Perfused Rat KidneyClinical Science, 1978
- MECHANICAL TRAUMA IN LEUKOCYTES1977
- On the Formation and Effects of Thromboxane A2 in Human PlateletsActa Physiologica Scandinavica, 1976
- Influence of Ureteral Catheter Size on Urinary Flow Rate and Glomerular Filtration Rate in the RatEuropean Journal of Clinical Investigation, 1976
- Some Observations on the Preparation of Platelet-Rich PlasmaThrombosis and Haemostasis, 1976
- Hematological changes in long-term perfusionJournal of Applied Physiology, 1962
- Development of an isolated perfused mammalian kidneyAmerican Journal of Physiology-Legacy Content, 1959
- DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTIONJournal of Biological Chemistry, 1949