ADVANCES IN THE LABORATORY DIAGNOSIS OF POLIOMYELITIS

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Abstract
The establishment of a definitive diagnosis by laboratory procedures in an illness produced by an infectious agent is desirable. Whether or not such a diagnosis may be achieved is dependent on the availability of appropriate techniques. In this instance availability has reference not only to the existence of diagnostic methods but also to the adaptability of the specific techniques to usage in routine diagnostic laboratories. Thus, with reference to the problem at hand, the definitive diagnosis of poliomyelitis, it is to be noted that in a restricted sense laboratory methods for diagnosis have been available since 1909 when Landsteiner and Popper produced an illness associated with paralysis in monkeys on inoculation with material obtained from a patient with poliomyelitis. However, with the primate as the only experimental animal, diagnostic assistance could not be given the clinician dealing with a suspected case of poliomyelitis. We will present here two developments in