Serum Level of Protein Bound Radioactive Iodine (I131) in the Diagnosis of Hyperthyroidism.
- 1 April 1949
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 70 (4) , 679-682
- https://doi.org/10.3181/00379727-70-17032
Abstract
The serum protein-bound radioactive iodine (I131) level was detd. 24 hrs. after the oral admn. of 150 microcuries of I131. 20 subjects were studied; 10 were thyrotoxic and 10 euthyroid. The protein-bound I131 was detd. by a modification of the method descr. by Chaikoff. (Endocrinology 40: 47. 1947). The serum protein-bound I131 in thyrotoxic patients was 38-146 x 10-5 microcuries/cc. (avg. 68). In euthyroid subjects the serum level ranged from 3-28 x 10-5 microcuries/cc. (avg. 13). It would appear that this test may be of diagnostic value as a measure of thyroid function.Keywords
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