Synthesis of a deuterium labeled variant of the rat hepatocarcinogen, methapyrilene
- 1 December 1987
- journal article
- research article
- Published by Wiley in Journal of Labelled Compounds and Radiopharmaceuticals
- Vol. 24 (12) , 1469-1477
- https://doi.org/10.1002/jlcr.2580241209
Abstract
No abstract availableKeywords
This publication has 9 references indexed in Scilit:
- The effect of chronic methapyrilene treatment on methapyrilene metabolism in vitroCarcinogenesis: Integrative Cancer Research, 1987
- Mutagenicity studies of selected antihistamines, their metabolites and products of nitrosationFood and Chemical Toxicology, 1986
- Carcinogenicity studies of some analogs of the carcinogen methapyrilene in F344 ratsZeitschrift für Krebsforschung und Klinische Onkologie, 1986
- Carcinogenicity of methapyrilene hydrochloride, mepyramine hydrochloride, thenyldiamine hydrochloride, and pyribenzamine hydrochloride in Sprague-Dawley ratsZeitschrift für Krebsforschung und Klinische Onkologie, 1986
- Chronic toxicity tests of pyrilamine maleate and methapyrilene hydrochloride in F344 ratsFood and Chemical Toxicology, 1984
- Failure of methapyrilene to induce tumors in hamsters or guinea pigsJournal of Toxicology and Environmental Health, 1983
- Trapping of metabolically generated electrophilic species with cyanide ion: metabolism of methapyrileneJournal of Medicinal Chemistry, 1981
- Liver Tumors Induced in Rats by Oral Administration of the Antihistaminic Methapyrilene HydrochlorideScience, 1980
- Heterocyclic Amines with Antihistaminic Activity1Journal of the American Chemical Society, 1946