Fatal Digitalis Poisoning
- 1 April 1973
- journal article
- Published by Wiley in Acta Pharmacologica et Toxicologica
- Vol. 32 (5) , 353-357
- https://doi.org/10.1111/j.1600-0773.1973.tb01481.x
Abstract
Two cases of digitalis poisoning are described. Case 1, a man, aged 40 years, swallowed for suicidal purposes about 50 digitalis tablets, each containing 50 mg standardized digitalis leaf, digitalis purpurea (0.5 i.u.). Death occured about 8 hours after the intake. A quantitative determination of digitalis glycoside in the gastric contents, and in the contents of the small intestine, blood and heart was performed with xanthydrol. Case 2, a child, 11 days old, because of a congenital heart disease was treated with digoxin. 1/2‐1 hour before death the child was given 0.7 mg digoxin intravenously. A quantitative determination of digoxin was performed with xanthydrol in the liver, heart and lung and by the fluorometric method in the liver, heart, kidney, urine and blood.Keywords
This publication has 14 references indexed in Scilit:
- Measurement of Plasma Digoxin Concentration by RadioimmunoassayBMJ, 1970
- DETERMINATION OF DIGITALIS IN BLOODActa Medica Scandinavica, 1970
- Determination of Therapeutic and Toxic Serum Digoxin Concentrations by RadioimmunoassayNew England Journal of Medicine, 1969
- Plasma and myocardial digoxin concentrations in patients on oral therapy.Heart, 1969
- Measurement of Digoxin in Plasma and its use in Diagnosis of Digoxin IntoxicationBMJ, 1969
- Forensic Chemical Detection of Digitalis GlycosidesPublished by Elsevier ,1969
- Colorimetric assay of digitoxin and gitoxin in mixtures after thin-layer chromatographic separationJournal of Chromatography A, 1969
- The measurement of digitoxin in human serum by radioimmunoassayJournal of Clinical Investigation, 1968
- Digoxin-specific antibodies.Proceedings of the National Academy of Sciences, 1967
- A Method for Measuring Plasma Levels of Digitalis GlycosidesCirculation, 1965