EFFECT OF NUTRITIONAL DEFICIENCIES ON HEPATIC INSULINASE IN RATS1

Abstract
The effect of various types of nutritional deficiency on hepatic insulinase was examined in rats. Deficiencies in protein, riboflavin and pantothenic acid were found to depress activity, whereas thiamine deficiency was without effect. Hepatic insulinase per gm. liver of normal rats increased with increasing age and weight of the animals.