A DISCUSSION OF THYROID PARAMETERS

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Abstract
Quantitative evaluation of thyroid function prior to the availability of radioactive iodine was limited. Several parameters were proposed for the estimation of I131 handling by the thyroid. These studies are discussed and their applicability is evaluated. The 24-hour uptake, I131 conversion ratio, and the saliva-PBI131 ratio are most commonly employed. Such tests do not have the same validity over the entire spectrum of thyroid dysfunction, and a critique is given of their use in clinical diagnosis. All thyroid functions are not inseparably linked, and one may vary without the others.