A Human Physiologically Based Pharmacokinetic Model for Trichloroethylene and Its Metabolites, Trichloroacetic Acid and Free Trichloroethanol
- 1 October 1998
- journal article
- clinical trial
- Published by Elsevier in Toxicology and Applied Pharmacology
- Vol. 152 (2) , 339-359
- https://doi.org/10.1006/taap.1998.8486
Abstract
No abstract availableKeywords
This publication has 40 references indexed in Scilit:
- Acute Intoxication with Trichloroethene: Clinical Symptoms, Toxicokinetics, Metabolism, and Development of Biochemical Parameters for Renal DamageToxicological Sciences, 1998
- A Physiologically Based Pharmacokinetic Model for Trichloroethylene and Its Metabolites, Chloral Hydrate, Trichloroacetate, Dichloroacetate, Trichloroethanol, and Trichloroethanol Glucuronide in B6C3F1 MiceToxicology and Applied Pharmacology, 1997
- Electrospray analysis of biological samples for trace amounts of trichloroacetic acid, dichloroacetic acid, and monochloroacetic acid.Journal of Analytical Toxicology, 1997
- A Trichloroethylene Risk Assessment Using a Monte Carlo Analysis of Parameter Uncertainty in Conjunction with Physiologically‐Based Pharmacokinetic ModelingRisk Analysis, 1995
- Pharmacokinetic Modeling of Trichloroethylene and Trichloroacetic Acid in HumansRisk Analysis, 1993
- Consideration of the Target Organ Toxicity of Trichloroethylene in Terms of Metabolite Toxicity and PharmacokineticsDrug Metabolism Reviews, 1991
- Liver tumor induction in B6C3F1 mice by dichloroacetate and trichloroacetateToxicology, 1990
- Metabolism of trichloroethylene by the isolated perfused lungToxicology and Applied Pharmacology, 1978
- Isolation, characterization and quantitation of chloral hydrate as a transient metabolite of trichloroethylene in man using electron capture gas chromatography and mass fragmentographyJournal of Pharmacy and Pharmacology, 1975
- Tissue Weights and Rates of Blood Flow in Man for the Prediction of Anesthetic Uptake and DistributionAnesthesiology, 1971