Postmortem Changes in Catecholamines, Indoleamines, and Their Metabolites in Rat Brain Regions: Prevention with 10‐kW Microwave Irradiation
- 1 September 1985
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 45 (3) , 935-939
- https://doi.org/10.1111/j.1471-4159.1985.tb04083.x
Abstract
Postmortem changes in catecholamines, indoleamines, and their metabolites in rat brain regions following decapitation were determined by LCEC. In the three regions studied neurotransmitter levels declined after decapitation, whereas the metabolite levels increased. Microwave irradiation at 10 kW rapidly inactivated brain enzymes and thus prevented the postmortem changes.Keywords
This publication has 12 references indexed in Scilit:
- Study of the Use of the Microwave Magnetic Field for the Rapid Inactivation of Brain EnzymesThe Japanese Journal of Pharmacology, 1983
- Estimation of the Turnover of 3‐Methoxytyramine in the Rat Striatum by HPLC with Electrochemical Detection: Implications for the Sequence in the Cerebral Metabolism of DopamineJournal of Neurochemistry, 1982
- Rapid tissue fixation by microwave irradiationTrends in Pharmacological Sciences, 1981
- Increase in dopamine in cerebral cortex and other regions of rat brain after microwave fixation: possible diffusion artifactBrain Research, 1978
- Use of microwave irradiation to prevent postmortem catecholamine metabolism: Evidence for tissue disruption artifact in a discrete region of rat brainBrain Research, 1978
- Rapid post mortem changes in 3,4‐dihydroxyphenylacetic acid (DOPAC), a dopamine metabolite, in rat striatumJournal of Neurochemistry, 1977
- Postmortem stability of norepinephrine, dopamine, and serotonin in rat brain1Journal of Neurochemistry, 1977
- REGIONAL STUDIES OF CATECHOLAMINES IN THE RAT BRAIN‐IJournal of Neurochemistry, 1966
- Changes in brain norepinephrine after decapitationBiochemical Pharmacology, 1966
- CHANGES IN THE 5‐HYDROXYTRYPTAMINE CONTENT OF RAT, RABBIT AND HUMAN BRAIN AFTER DEATHBritish Journal of Pharmacology and Chemotherapy, 1962