A Human Monoclonal Antibody to rhG
- 1 April 1986
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 50 (3) , 160-163
- https://doi.org/10.1111/j.1423-0410.1986.tb04870.x
Abstract
Hybridomas secreting a human monoclonal IgG1 antibody against a variant of the rhG antigen were produced from B lymphocytes of an Rh-negative donor with serum antibodies to D and C antigens. The antibody reacts by indirect hemagglutination with nearly all C- or D-positive cells, confirming the strong association in the expression of G with D or C antigens. The lack of antibody reactivity to C-negative Du cells suggests a particular epitope on the D complex associated with the G antigen.This publication has 10 references indexed in Scilit:
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