HLA Antigen Distribution and HLA Haplotype Segregation in Crohn's Disease

Abstract
A study of the HLA—A, —B, —C, and —DR antigens in patients with Crohn's disease and controls did not reveal a significant strong association with a particular HLA antigen. A segregation analysis of parental HLA haplotypes in nine families with at least two children suffering from Crohn's disease did not show a significant deviation from the expected Mendelian segregation.