Platelet Preservation

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Abstract
THE usefulness of platelet transfusions seems well established in certain disorders, notably acute leukemia.1 The ultimate place of platelet transfusions in clinical medicine will depend upon their availability, which in turn will further define their usefulness, as data are collected on the frequency with which isoimmunization limits their therapeutic efficacy.2 3 4 For the past ten years EDTA-anticoagulated whole blood has been used extensively in the preparation of platelet concentrates for clinical use. Its chief disadvantage has been the limited storage time of EDTA red blood cells. Its only advantage, the prevention of platelet aggregation (clumping) in platelet concentrates, has been superseded . . .