Synthesis of Sucrose 4′-(L-Arabinose-2-YL Phosphate) (Agrocinopihe A) Using an Arabinose 2-H-Phosphonate Intermediate
- 1 December 1988
- journal article
- research article
- Published by Taylor & Francis in Journal of Carbohydrate Chemistry
- Vol. 7 (4) , 749-755
- https://doi.org/10.1080/07328308808058942
Abstract
The first completed chemical synthesis of Agrocinopine A (5) is presented. The key step in the synthesis was the pivaloyl chloride promoted condensation of a blocked arabinose 2-H-phosphonate derivative 3 with a protected sucrose derivative 1 having a free hydroxyl at 4′-OH. The resulting H-phosphonic acid diester was oxidised in situ with iodine to produce the corresponding phosphodiester 4, which was subsequently deblocked to give Agrocinopine A.This publication has 11 references indexed in Scilit:
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