Relationship between Intake of Vitamin B12 and Its Storage by the Kidney in the Rat
- 1 June 1962
- journal article
- research article
- Published by Elsevier in Journal of Nutrition
- Vol. 77 (2) , 131-136
- https://doi.org/10.1093/jn/77.2.131
Abstract
The role of the kidney in the turnover of administered radioactive vitamin B12 was studied in rats. It was found that, unlike other organs, the kidney has a large capacity for storing vitamin B12 that has been absorbed in excess of the body requirement, and releases it later. The kidney also has a unique function of sparing its share when the demand for this vitamin in the body is great. The liver is very different from the kidney in this respect, and cannot be regarded as a storage organ of vitamin B12 in the same sense.Keywords
This publication has 13 references indexed in Scilit:
- Renal Clearance of Intravenously Administered Vitamin B12Experimental Biology and Medicine, 1961
- Effect of Food Restriction on Tissue Uptake and Urinary Excretion of Co60-Labeled Cyanocobalamin by Various AnimalsJournal of Nutrition, 1961
- Stability of Injected Vitamin B12-Co60 and Vitamin B12 Content of Dog LiverExperimental Biology and Medicine, 1960
- Vitamin B12 absorption in rats, studied by a ‘loop’ techniqueAmerican Journal of Physiology-Legacy Content, 1960
- Intracellular Distribution of Vit. B12-Co60 in Liver and Kidney of B12 Deficient and Normal Rats.Experimental Biology and Medicine, 1959
- The Uptake and Turnover of Radioactive Vitamin B12 in Rabbit TissuesJournal of Nutrition, 1959
- Organ, Urine and feces Vitamin B12 Content of Normal and Starved RabbitsJournal of Nutrition, 1958
- Fractionation of Radioactive B12-Complex In Kidney Homogenates.Experimental Biology and Medicine, 1957
- Effect of Carbon Tetrachloride Injury on Plasma and Liver Vitamin B12 LevelsExperimental Biology and Medicine, 1957
- Coprophagy in the RabbitNature, 1940