NIPPOSTRONGYLUS-BRASILIENSIS INFECTION IN RATS - CELLULAR REQUIREMENT FOR WORM EXPULSION
- 1 January 1977
- journal article
- research article
- Vol. 32 (4) , 521-528
Abstract
The expulsion of antibody-damaged N. brasiliensis nematodes from the intestine of rats irradiated with 750 rad 60Co was induced by thoracic duct lymph (TDL) or mesenteric lymph node (MLN) cells apparently without the help of bone marrow-derived cells. The effector cells were present in the TDL or MLN of rats by the 8th day after infection and could be recovered from the peritoneal cavity. The ability of TDL cells to transfer immunity to irradiated recipients was undiminished when the cells with immunoglobulin on their surface were removed. Following antibody damage this nematode is apparently expelled by nonimmunoglobulin-bearing lymphocytes which are effective in the absence of newly formed cells derived from the cell recipients.This publication has 19 references indexed in Scilit:
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