REDUCTION IN SEVERITY OF ACUTE RENAL-FAILURE (ARF) IN RATS BY DOPAMINE

  • 1 January 1977
    • journal article
    • letter
    • Vol. 27  (4) , 137-139
Abstract
Dopamine was administered to rats at the time of initiation of anoxic acute renal failure [ARF]. Dopamine partially reduced the severity of ARF as evidenced by a reduction in blood urea, serum creatinine and an increase in glomerular filtration rate (GFR). UNaV [urinary Na excretion/min] in dopamine treated ARF was similar to sham operated animals, and both were significantly lower than control ARF.