Circulating Anti-AHG Anticoagulant in a Patient with Lupus Erythematosus Disseminatus
- 1 January 1962
- journal article
- research article
- Published by S. Karger AG in Acta Haematologica
- Vol. 28 (3) , 155-162
- https://doi.org/10.1159/000207259
Abstract
A patient with disseminated lupus erythematosus developed severe bleeding manifestations. A study of the hemostatic mechanism revealed prolongation of the bleeding time and the presence of a circulating anticoagulant inhibiting antihemophilic globulin. ACTH and Prednisolone failed to improve the clinical picture and the laboratory findings. The administration of a cephalin complex intravenously improved the bleeding manifestations and corrected in part the clotting anomaly for a period of 48 hours.Keywords
This publication has 5 references indexed in Scilit:
- Effects of Cephalin on the Hemostatic Defect of the Hemophilia Syndrome in vitro and in vivoActa Haematologica, 1961
- Studies on Platelets XXIII. A Cephalin Complex and its Fractions in the Management of Thrombocytopenic Bleeding. Studies in vitro and in vivoActa Haematologica, 1961
- Stuart Clotting Defect. I. Segregation of an Hereditary Hemorrhagic State from the Heterogeneous Group Heretofore Called “Stable Factor” (SPCA, Proconvertin, Factor VII) DeficiencyJournal of Clinical Investigation, 1957
- Acquired Circulating Anticoagulants in Systemic "Collagen Disease"Blood, 1955
- The Control of Dicumarol Therapy and the Quantitative Determination of Prothrombin and ProconvertinScandinavian Journal of Clinical and Laboratory Investigation, 1951