SYMPATHOMIMETIC AMINES: THE RELATION OF STRUCTURE TO THEIR ACTION AND INACTIVATION
- 1 April 1946
- journal article
- review article
- Published by American Physiological Society in Physiological Reviews
- Vol. 26 (2) , 169-197
- https://doi.org/10.1152/physrev.1946.26.2.169
Abstract
The purpose of this article is to review the formation of pressor amines in the body, and their relation to the pathogenesis and exptl. alleviation of hypertension; to consider their pharmacodynamic effects on cellular or tissue metabolism as determining the mode of action of these agents; to review the relation of structure to the inactivation of sympathomimetic amines; and to present certain generalizations concerning the relation of structure of these com- pounds to their action and inactivation.Keywords
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