Cellular immunity in experimental glomerulonephritis of rats. I. Delayed hypersensitivity and lymphocyte stimulation studies with renal tubular antigens.

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  • 1 May 1971
    • journal article
    • Vol. 20  (5) , 755-66
Abstract
Experimental glomerulonephritis (EGN) was produced in Sprague-Dawley rats with a single intradermal injection of a renal tubular fraction called Fx1A. Presence of disease was confirmed by proteinuria and by light and electron microscopic changes. This antigen and also the non-nephritogenic antigen, Fx1B, were used to study cellular immunity in nephritic and three groups of control rats.