TGI-Simulator: A visual tool to support the preclinical phase of the drug discovery process by assessing in silico the effect of an anticancer drug
- 1 February 2012
- journal article
- Published by Elsevier in Computer Methods and Programs in Biomedicine
- Vol. 105 (2) , 162-174
- https://doi.org/10.1016/j.cmpb.2011.09.001
Abstract
No abstract availableKeywords
This publication has 14 references indexed in Scilit:
- The Role of Pharmacokinetic and Pharmacokinetic/Pharmacodynamic Modeling in Drug Discovery and DevelopmentFuture Medicinal Chemistry, 2010
- Testing additivity of anticancer agents in pre-clinical studies: A PK/PD modelling approachEuropean Journal Of Cancer, 2009
- Re: Antitumor Efficacy Testing in RodentsJNCI Journal of the National Cancer Institute, 2009
- Modeling of tumor growth and anticancer effects of combination therapyJournal of Pharmacokinetics and Pharmacodynamics, 2009
- A Minimal Model of Tumor Growth InhibitionIEEE Transactions on Biomedical Engineering, 2008
- Predicting the active doses in humans from animal studies: A novel approach in oncologyEuropean Journal Of Cancer, 2007
- A mathematical model to study the effects of drugs administration on tumor growth dynamicsMathematical Biosciences, 2006
- Mathematical modeling of tumorigenesis: mission possibleCurrent Opinion in Oncology, 2005
- Predictive Pharmacokinetic-Pharmacodynamic Modeling of Tumor Growth Kinetics in Xenograft Models after Administration of Anticancer AgentsCancer Research, 2004
- Role of modelling and simulation in Phase I drug developmentEuropean Journal of Pharmaceutical Sciences, 2001