Further Studies Concerning the Placental Transfer of Fluoride in the Rat

Abstract
Female rats were given 25 ppm fluoride as various fluoride compounds during gestation or 25 ppm fluoride as NaF during gestation and a pregestational period. Offspring were killed at birth and analyzed for fluoride. Fluoride compounds given during gestation resulted in comparable amounts of fluoride in the offspring, but a greater amount was observed in pups whose mothers received ZrOGeF6. Pregestational fluoride exposure increased the amount of transplacental fluoride transfer.

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