Lymphocytic Response of Normal Individuals to Transient Hyper- and Hypoglycemia

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Abstract
Intraven. admn. of 25 g. of glucose in 50% soln. was accompanied by a significant lymphocytopenia which reached its lowest level at 30 min. to 1 hr. in 5 normal subjects, and in 2 hrs. in the 6th. Intraven. admn. of 0.075 units/kg. of body wt. evoked a significant absolute lymphocytosis which reached its peak in 45-50 min. in 7 normal persons and in 120 min. in the 8th. This study suggests that the response of the adrenal cortex to hyper- and hypoglycemia serves to maintain homeostasis.

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