Phosphorus Metabolism of the Adrenal Gland of the Rat

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Abstract
Observations were made on the incorporation of inorganic phosphate labeled with P32 into the inorganic P, 20-minute hydrolyzable P and total acid-soluble P of the adrenal gland of rats either maintained at room temperature (22 ± 1°C) or conditioned to cold (3 ± 1°C). In confirmation of previous findings, there was an increase in the incorporation of inorganic P32 into the acid-soluble P of the adrenal of the rats maintained in the cold. Exposure to more severe cold (–5°C) for 2 hours, caused a great increase in the incorporation of inorganic P32 into the acid-soluble P of the adrenal of the nonacclimatized rats, compared to a slight, and statistically insignificant, increase in the acclimatized animals. The adrenal response to cold in the nonacclimatized rats was greatly decreased by the prior administration of cortisone.