Hematology

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Abstract
The SpleenIN its normal state, the spleen is a relatively small organ weighing 50 to 100 gm. and containing a variable amount of blood. Its function as a reservoir was thoroughly studied twenty-one years ago by Barcroft et al.1 Removal of the normal spleen is followed by a number of interesting blood changes2—a tendency toward an increase in the red-cell count, the development of thin red cells (target cells) with increased hypotonic resistance, the development of Howell—Jolly bodies (nuclear remains) in the red cells and increases in the white-cell and platelet counts. These changes indicate a definite relation . . .
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